reframe
About this compound

IGF-1 LR3 (Long-R3 IGF-1) is a synthetic 83-amino-acid analogue of insulin-like growth factor 1 with 13 additional residues at the N-terminus and an arginine substitution at position 3. These modifications dramatically reduce binding to IGF-binding proteins, keeping the peptide in its active, unbound form.

The result is a longer-acting molecule (~20 h half-life) with stronger downstream IGF-1 receptor activation than native IGF-1.

Research applications
  • IGF-1 receptor activation studies
  • Protein and lipid synthesis research
  • Cell proliferation, differentiation, and survival models
  • Nerve regeneration and muscle-wasting investigation
Storage

Lyophilized vial stable at 2–8 °C; -20 °C for long-term storage. Reconstitute with sterile bacteriostatic water; use reconstituted solution within one week at 2–8 °C.

For research and laboratory use only. Not for human or veterinary consumption.

The Protocol

How to run this compound.

01
Reconstitute

Add bacteriostatic water to the sealed vial. Swirl — do not shake. Refrigerate after reconstitution.

02
Dose

Reconstitute with bacteriostatic water. Subcutaneous administration on protocol cadence.

03
Cadence

Run on the protocol schedule. The system rewards consistency over intensity.

04
Stack

Pair with complementary REFRAME lines. See suggestions below.